The Pomurska statistical region had 5.4% of Slovenia’s population in 2021. The region stood out with the highest natural decrease (5.9 per 1,000 population) and the lowest share of foreign citizens in the population (2.5%). The age structure of the population was the least favourable here. The share of young people (aged 0–14) in this region was the lowest at 13.1% and the share of population aged 65 or more was the highest (24.0%). The mean age of the population in the Pomurska statistical region was the highest in Slovenia (46.1 years). Residents of this region were on average 3.9 years older than in the Osrednjeslovenska statistical region, where the mean age of the population was the lowest. Life expectancy at birth was the lowest for boys and second lowest for girls. Boys born in 2021 in this region can expect to live 75.8 years, while girls can expect to live 82.0 years. The number of divorces per 1,000 population was higher than in most of the other regions (1 per 1,000 population). The educational structure of the population was also less favourable. Almost a third of the population had only basic education or less. This region has the second highest share of children aged 1–5 included in kindergartens (82.7%).

Residents of Pomurska assessed general satisfaction with their life with the lowest average score of 7.3 out of 10. The share of households that received financial or material assistance from charities in this region was second highest, namely 6%; it was only higher in Zasavska (8%). Dwellings that were in bad condition (problems such as a leaking roof, damp walls/floors/foundation, or rot in window frames or the floor) were inhabited by 24% of households, which was the second highest share among the regions. On the other hand, the region had the second lowest overcrowding rate; 8.1% of people lived in dwellings with too few rooms for the number of household members.

In the Pomurska statistical region, 3.7% of the national GDP was generated in 2021. GDP per capita amounted to EUR 16,920, 31.7% less than the average in Slovenia. The region had about 8,000 enterprises, which on average employed 4.3 people. The employment rates for men (61.7%) and women (56.0%) were the lowest in Slovenia.