This coastal statistical region with the sub-Mediterranean climate is the only one with an exit to the sea. Natural features enable the development of tourism, transport and special agricultural crops.

Three quarters of gross value added are created by services. In 2010, trade, accommodation and transport activities contributed the highest share – more than a third – of gross value added in the region; most of it was created by activities in the Port of Koper and the seaside and spa tourism. The Obalno-kraška region recorded almost a quarter of all tourist overnights in the country in 2011; slightly less than half by domestic tourists. As regards foreign tourists, Italians, Austrians and Germans predominated. Agricultural holdings in this region are among the smallest in Slovenia. Growing permanent crops is an important branch of agriculture in the Obalno-kraška region; permanent crops represent more than a quarter of total utilised agricultural area in this region. Organic farming represents more than a tenth of total utilised agricultural area in the region, which is twice as high as at the national level.

The increase in the number of inhabitants in the Obalno-kraška region was in 2011 again the result of new immigration from abroad. In the beginning of 2012 every thirteenth person living in the region was a foreign national; four out of five foreign immigrants were citizens of one of the former Yugoslav republics.