Municipality Semič, which is part of the Jugovzhodna Slovenija statistical region, measures 147 km2; this ranks it 42nd among Slovene municipalities.

Statistical data for 2010 reveal the following:

In the middle of 2010 about 3,850 people (about 1,900 men and 1,950 women) were living in the municipality, which ranks Semič 131st among Slovene municipalities. The population density was 26 people per square kilometre, which was lower than the national average of 101 people per square kilometre.

The number of live births was higher than the number of deaths, which means that natural increase per 1,000 population in the municipality was positive. It was 3.9 (in Slovenia 1.8). The number of people who moved from the municipality was lower than the number of people who moved into the municipality, so net migration per 1,000 population in the municipality was positive. It was 17.7. The sum of natural increase and net migration per 1,000 population in the municipality was positive. It was 21.6 (in Slovenia 1.6).

The mean age of people in Semič was 41.3 years, which was lower than the national average (41.6).

As in most Slovene municipalities, in Semič the number of old people was higher than the number of young people: there were 103 people, aged 65 or more, per 100 people aged 0–14. This ratio shows that the value of the ageing index was lower than the national average of 117. It also shows that the mean age of people in Semič is growing more slowly than in Slovenia as a whole. Data by sex show that the ageing index for women was in all Slovene municipalities higher than the ageing index for men. In Semič – as in most Slovene municipalities – more women were 65+ years old than 14 or less; for men the situation was exactly the opposite.

Semič had 1 kindergarten. It was attended by 133 children or 72% of all children aged 1–5, which was less than the national average of 74%. In the school year 2010/2011 elementary schools in Semič were attended by about 320 pupils, while various upper secondary schools were attended by about 190 pupils. There were 53 students and 11 graduates per 1,000 people in the municipality; in Slovenia the averages were 52 per 1,000 and 10 per 1,000, respectively.

Among people aged 15–64 (i.e. working age population) about 57% were persons in employment (i.e. persons in paid employment or self-employed persons), which is less than the national average of 59%.

The registered unemployment rate was 13.9%, which is more than the national average (10.7%). As in most Slovene municipalities, more women than men were unemployed.

In Semič, average monthly gross earnings per person employed by legal persons were about 23% lower than the annual average of monthly earnings for Slovenia; and net earnings about 19% lower.

Every 27th person in the municipality was receiving at least one financial social assistance. In Slovenia as a whole every 22nd person received at least one financial social assistance.

The value of gross investment in new fixed assets in the municipality (EUR 987 per capita) was lower than the national average (EUR 2,176 per capita).

In 2010, there were 425 dwellings per 1,000 population. About 51% of dwellings had at least three rooms. Average size of dwellings in the municipality was 73 m2.

Every other person in Semič had a car (50 passenger cars per 100 population); cars in this municipality were on average 9 years old.

In 2010, 360 kg of municipal waste per person was collected in Semič, which is 29 kg less than on average in Slovenia.